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2 546 249

(13)

(51)

IPC

C12N15/29(2006-01-01)

C12N5/71(2010-01-01)

C12N5/16(2006-01-01)

C12N15/63(2006-01-01)

C07K2/00(2006-01-01)

C07K14/75(2006-01-01)

C07K14/525(2006-01-01)

C07K14/195(2006-01-01)

(21) (22)

Application

2013136874/10, 2013-08-07

(24)

Start date

2013-08-07

(22)

Actual filing date

2013-08-07

(45)

Published

2015-04-10

(72)

Inventor

Ataullakhanov Ravshan InojatovichAtaullakhanov Rustam RavshanovichBagaev Aleksandr VladislavovichGintsburg Aleksandr LeonidovichLogunov Denis Jur'EvichNaroditskij Boris Savel'EvichPichugin Aleksej Vasil'EvichSedova Elena SergeevnaTutykhina Irina LeonidovnaTukhvatulin Amir Il'DarovichKhaitov Rakhim MusaevichShmarov Maksim Mikhajlovich

(73)

Holder

Silezia Grup Pte. Ltd.Ataullakhanov Rustam Ravshanovich

COMPOSITION FOR AMPLIFICATION OF TRANSGENE EXPRESSION IN EUCARIOTIC CELLS, AND METHOD FOR INCREASING GENERATION OF TARGET PROTEIN CODED WITH TRANSGENE Russian patent published in 2015 - IPC C12N15/29 C12N5/71 C12N5/16 C12N15/63 C07K2/00 C07K14/75 C07K14/525 C07K14/195

Abstract RU 2546249 C2

FIELD: biotechnologies.

SUBSTANCE: invention relates to compositions for intensive generation of a target protein in eucariotic cells, which includes a DNA vector with an insert of target protein gene and an agonist of cell receptors. Besides, the invention relates to methods for increasing generation of a target protein coded with a transgene in eucariotic cells by using the above compositions.

EFFECT: invention allows effective increase of generation of a target protein in eucariotic cells.

28 cl, 4 dwg, 7 tbl, 10 ex

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RU 2 546 249 C2

Authors

Ataullakhanov Ravshan Inojatovich

Ataullakhanov Rustam Ravshanovich

Bagaev Aleksandr Vladislavovich

Gintsburg Aleksandr Leonidovich

Logunov Denis Jur'Evich

Naroditskij Boris Savel'Evich

Pichugin Aleksej Vasil'Evich

Sedova Elena Sergeevna

Tutykhina Irina Leonidovna

Tukhvatulin Amir Il'Darovich

Khaitov Rakhim Musaevich

Shmarov Maksim Mikhajlovich

Dates

2015-04-10—Published

2013-08-07—Filed