FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry - obtaining derivatives of 3-furylpropane-1-on derivatives of formula 1a-j, where R1-R4 have following values:
which involves reaction of 2-methylfuran with available α,β-unsaturated carbonyl compounds in presence of copper (II) bromide in 1,2-dichloroethane at room temperature during 4 hours.
EFFECT: these compounds are of interest in synthesis of pharmaceutical substances.
1 cl, 2 tbl, 11ex
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Authors
Dates
2016-11-20—Published
2015-11-02—Filed