FIELD: chemistry.
SUBSTANCE: invention relates to a method for preparation of 3-(2-furyl)phthalide derivatives of formula 1 that are of interest as starting compounds for synthesis of a number of biologically active and promising biological screening heterocyclic systems. Method comprises thermostating available mixture of 2-formylbenzoic acid and 2-methylfuran at 60 to 80 °C in water with stirring for 3-7 days. For compounds 1b-f reaction is carried out at 80 °C, for 1a - at 65 °C, for 1g - at 60 °C.
EFFECT: simple process by avoiding use of an acid catalyst and solvent dioxane.
1 cl, 2 tbl, 10 ex
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