PHARMACEUTICAL COMPOSITION OF N-(6-PHENYLHEXANOYL)GLYCYL-L-TRYPTOPHAN AMIDE IN SOLID DOSAGE FORM Russian patent published in 2016 - IPC A61K31/405 A61K38/05 A61K47/00 A61K9/20 A61K9/48 A61J3/00 A61P25/22 A61P29/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to pharmacy, and concerns pharmaceutical composition in solid dosage form and containing therapeutically effective amount of N-(6-phenylhexanoyl)glycyl-L-tryptophan amide as medicinal substance, and auxiliary substances, which are binding agent of group of substances providing sufficient weight of tablet or capsule: cellulose or cellulose derivatives, such as microcrystalline cellulose; lactose, polyvinylpyrrolidone, calcium carbonate, calcium phosphate; auxiliary substances with high sorption capacity: colloidal silica, magnesium aluminometasilicate; group of sliding agents - stearic acid and/or its salts, surfactants: sodium oleate, sodium lauryl sulphate; disintegrants from group: starch, pectin, polyvinyl pyrrolidone, sodium croscarmellose, sodium carboxymethyl cellulose.

EFFECT: tablets and capsules meet all requirements of State Pharmacopeia XI and XII edition and have high bioavailability of above therapeutic peptide.

1 cl, 3 dwg, 2 tbl, 16 ex