FIELD: hygiene.
SUBSTANCE: group of inventions relates to oral care formulations and their application. Disclosed oral care composition comprises: a fluoride ion source; poly(propylene oxide)/poly(ethylene oxide) copolymer, in an amount of from 2 to 10 %, by weight, of the composition; fumaric acid in an amount effective to enhance delivery of fluoride to the enamel, namely, in an amount of from 0.01 to 0.25 %, of the total composition weight. There are also: method of enhancing delivery of fluoride to tooth enamel and method of enhancing protection of teeth against caries and cavities and increasing resistance to acid demineralization, comprising administering to the oral cavity of a subject in need thereof; use of said composition for enhancing protection of teeth against caries and cavities and increasing resistance to acid demineralization, as well as for manufacture of a medicament of similar purpose.
EFFECT: using the group of inventions provides higher biological availability of fluoride in the oral care formulations, as well as enhanced fluoride uptake and remineralization of enamel surfaces using these formulations.
19 cl, 5 tbl, 5 ex
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Authors
Dates
2016-11-27—Published
2011-12-20—Filed