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2 835 237

(13)

(51)

IPC

C01F11/00(2006-01-01)

C01B25/32(2006-01-01)

B82B3/00(2006-01-01)

B82Y30/00(2011-01-01)

A61L27/12(2006-01-01)

A61K6/75(2020-01-01)

(21) (22)

Application

2024123062, 2024-08-12

(24)

Start date

2024-08-12

(22)

Actual filing date

2024-08-12

(45)

Published

2025-02-24

(72)

Inventor

Tarasov Igor AleksandrovichTrubitsyn Mikhail AleksandrovichFurda Liubov Vladimirovna

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniia Gosudarstvennyi Natsionalnyi Issledovatelskii Universitet"

METHOD OF PRODUCING NANOSIZED CALCIUM-DEFICIENT SILICATE- AND FLUORINE-SUBSTITUTED HYDROXYAPATITE Russian patent published in 2025 - IPC C01F11/00 C01B25/32 B82B3/00 B82Y30/00 A61L27/12 A61K6/75

Abstract RU 2835237 C1

FIELD: medicine.

SUBSTANCE: invention relates to creation of new biomaterials for medical purposes, namely to production of single-phase nanosized biomimetic hydroxyapatite, doped with silicate- and fluoride-anions of formula Ca_10-d(PO₄)_6-y(SiO₄)_y(OH)_2-y-z-2dF_z·nH₂O, where d is the degree of deficiency of calcium ions Ca²⁺, y is coefficient or degree of substitution of phosphate anions with silicate anions, z is the coefficient or degree of substitution of hydroxide anions with fluoride anions, with molar ratio Ca²⁺/PO₄^3-+SiO₄^4-<1.67 and molar ratio of fluoride anions to silicate anions of 0 to 2. Biomaterial can be used for production of bioactive dental filling materials, as well as for other dental and surgical applications.

EFFECT: method enables to obtain said hydroxyapatite with controlled bioresorbability and osteoinductance.

1 cl, 5 dwg, 2 tbl, 3 ex

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RU 2 835 237 C1

Authors

Tarasov Igor Aleksandrovich

Trubitsyn Mikhail Aleksandrovich

Furda Liubov Vladimirovna

Dates

2025-02-24—Published

2024-08-12—Filed