COMPOSITION FOR REDUCTION OF TRPA1 AND TRPV1 SENSATIONS Russian patent published in 2016 - IPC A61K8/22 A61K8/34 A61K8/30 A61Q5/10 A61Q11/00 

FIELD: hygiene.

SUBSTANCE: invention relates to personal care compositions: a) at least 0.2 % by weight of personal care composition hydrogen peroxide and/or 0.5 % by weight of personal care composition menthol; b) at least one of an antagonist to TRPA1 receptor or an antagonist to TRPV1 receptor, wherein TRPA1 antagonist is at least one of cinnamon bark oil; γ-dodecalactone; vanillic acid; γ-methyl decalactone; trans,trans-2,4-nonadienal; 4-allyl-2,6-dimethoxyphenol; o-methoxycinnamaldehyde; 4-methyl-2-phenyl-2-pentenal (mixture of cis and trans); 2-methoxy-4-propyl-phenol; methyl-2-methoxy-benzoate; δ-tetradecalactone; 1-methyl-2-pyrole carboxaldehyde; 3,3,5-trimethylcyclohexanol; N-(2-hydroxyethyl)lactamide; 2-(3-phenylpropyl)tetrahydrofuran; anisyl butyrate; methyl-4-phenyl butyrate; 3-heptyldihydro-5-methyl-2(3H)-furanone; 3-acetylsulfanylhexyl acetate; 3-methyl-5-propyl-2-cyclohexen-1-one; isobornyl isobutyrate; bornyl valerate; citronellyl acetate; (2S,5S,6S)-6-)hydroxy- dihydrotheaspirane; or trans-2-hexenal; and antagonist to TRPV1 is at least one of (-)-bornyl acetate; hydroxycitronellal; apritone; methyl-N,N-dimethylanthranilate; 2-ethoxy-3-ethylpyrazine; L-piperiton; isobornyl isobutyrate; 4-acetoxy-2,5-dimethyl-3(2H)-furanone; tripropylamine; dihydrojasmone; 1-methyl-2-pyrole carboxaldehyde; 3-octyl acetate; 2-methylbutylisovalerate; jasminone; piperonyl isobutyrate; phenoxyethyl propionate; vanillin propylene glycol acetate; octenyl cyclopentanone; butyl isobutyrate; guaiacwood oil; or tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran.

EFFECT: invention ensures reduction of negative sensations of burning, irritation, warming, related to presence of menthol and/or hydrogen peroxide in personal care compositions.

12 cl, 15 ex, 22 tbl