4-N-[(DIHYDROXYPHOSPHORYL)METHYL]-6-(CHLOROMETHYL)-1,4,2-OXAZAPHOSPHORINANE AND METHOD FOR PRODUCTION THEREOF Russian patent published in 2016 - IPC C07F9/547 

Abstract RU 2605556 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing 4-N-(dihydroxyphosphoryl)methyl-6-(chloromethyl)-1,4,2-oxazaphosphorinane, which can be used as organic semi-finished product for synthesis of polyfunctional chelants, of formula: . Proposed method comprises reaction of tetrasodium salt iminobis(methylphosphonic acid) with epichlorohydrin, taken in excess of 10 %, in an aqueous medium at room temperature with subsequent acidification of reaction mass and separation from evaporated reaction solution of end product by non-methanol precipitation with subsequent filtration of sediment of desired compound. Cleaning of 4-N-(dihydroxyphosphoryl)methyl-6-(chloromethyl)-1,4,2-oxazaphosphorinane is performed by recrystallization of glacial acetic acid. Precipitate is filtered and recrystallised from glacial acetic acid.

EFFECT: novel efficient method of producing a promising chemical product.

3 cl, 1 ex

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RU 2 605 556 C1

Authors

Tsirulnikova Nina Vladimirovna

Bolt Jaroslav Vasilevich

Fetisova Tatjana Sergeevna

Dates

2016-12-20Published

2015-12-03Filed