METHOD OF PRODUCING A MEDICINAL PREPARATION BASED ON HUMAN CELL VESICLES Russian patent published in 2016 - IPC A61K35/12 A61P9/10 

Abstract RU 2605853 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine and concerns a method of producing a medicinal agent based on human vesicles for stimulation of angiogenesis in patients with ischemic tissue damage, where human cells of line SH-SY5Y are grown on culture bottle, washed by isotonic buffer solution, sterile solution of cytochalasin B added to the cells, cells are washed with isotonic buffer solution, transferred into suspension, subjected to active mixing and a series of centrifugations carried out to produce the declared drug.

EFFECT: invention provides preparing of the therapeutic agent, having increased in comparison with the prototype and analogues therapeutic action and angiogenic potential, as well as meets criterion of the biological safety.

1 cl, 1 ex, 5 dwg

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RU 2 605 853 C1

Authors

Gomzikova Marina Olegovna

Zhuravleva Margarita Nikolaevna

Pestel Richard Georg

Rizvanov Albert Anatolevich

Dates

2016-12-27Published

2015-07-27Filed