APPLICATION OF MEMBRANE VESICLES OF MULTIPOTENT STROMAL CELLS INDUCED BY B CYTOCHALASIN, FOR RESTORATION AND INCREASE OF MITOCHONDRIAL FUNCTION Russian patent published in 2020 - IPC A61K35/28 C12N5/00 

Abstract RU 2727540 C1

FIELD: biotechnology.

SUBSTANCE: invention refers to biotechnology, namely to application of membrane vesicles of multipotent stromal cells for restoration and enhancement of mitochondrial function by delivering functionally active mitochondria into cells of mammals for therapy of mitochondrial dysfunction.

EFFECT: membranous vesicles of multipotent stromal cells are induced by cytochalasin B, surrounded by bilipid cytoplasmic membrane, carry superficial cytoplasmic receptors (CD90, CD29, CD44, CD73), have diameter ranging from 100 to 2,000 nanometers and contain functionally active mitochondria.

1 cl, 8 dwg

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RU 2 727 540 C1

Authors

Kurbangaleeva Sirina Vasilevna

Gomzikova Marina Olegovna

Rizvanov Albert Anatolevich

Dates

2020-07-22Published

2019-11-22Filed