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(19)

RU

(11)

2 606 753

(13)

C1

(51)

IPC

C07K5/11(2006-01-01)

C07K5/113(2006-01-01)

C07K7/06(2006-01-01)

A61K38/07(2006-01-01)

A61K38/08(2006-01-01)

A61P17/02(2006-01-01)

A61K8/64(2006-01-01)

A61Q19/00(2006-01-01)

A61Q19/08(2006-01-01)

(21) (22)

Application

2015138925, 2014-01-21

(24)

Start date

2014-01-21

(22)

Actual filing date

2014-01-21

(45)

Published

2017-01-10

(72)

Inventor

Chzhan LitszyuanKarmajkl Robin

(73)

Holder

Kheliks Bajomediks, Ink.

SHORT BIOLOGICALLY ACTIVE PEPTIDES FOR ACCELERATING WOUND HEALING Russian patent published in 2017 - IPC C07K5/11 C07K5/113 C07K7/06 A61K38/07 A61K38/08 A61P17/02 A61K8/64 A61Q19/00 A61Q19/08 

Abstract RU 2606753 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, namely to cell technologies, and can be used for skin care or for treating skin wounds or mucous membrane tissue of mammal. Following peptides are obtained: EKMG, MGRN and KMGRN – short fragments of peptide HB-107 (MPKEKVFLKIEKMGRNIRN), which itself is fragment of antimicrobial protein cecropin B and exhibits properties of cell migration stimulation. Peptides can be amidated at C-end or lipidized at N-end.

EFFECT: present invention enables to obtain peptide with improved activity in human skin fibroblasts stimulation compared to peptide HB107 – cecropin B fragment.

16 cl, 3 tbl, 4 ex

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RU 2 606 753 C1

Authors

Chzhan Litszyuan

Karmajkl Robin

Dates

2017-01-10—Published

2014-01-21—Filed

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