FIELD: medicine.
SUBSTANCE: invention relates to medicine. Method of determining probability of recurrent breast cancer in mammal is disclosed, which involves measurement of levels of expression of RNA-transcripts KI67, CCND1, PTEN, NDRG1, TERT in biological sample containing tumor cells and determining recurrence factor for specified subject with due allowance for measured gene expression level as point on curve with two coordinates X and Y. If value of which is within X<0.9; Y<-0.2 maximum risk of recurrence through 0–30 months is determined. If value of which is within X<0.3; Y>-0.1 maximum risk of recurrence through 30–60 months is determined. If the value of which is within X>1; Y – any, minimum risk of recurrence is determined.
EFFECT: higher precision and reproducibility of method of determination of recurrent breast cancer.
9 cl, 2 dwg, 11 tbl, 3 ex
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