MEDICAL PREDICTION AND PREDICTION OF TREATMENT RESULTS USING ACTIVITY OF MULTIPLE CELL SIGNALING PATHWAYS Russian patent published in 2020 - IPC G01N33/48 C12Q1/6886 

FIELD: medicine; bioinformatics.

SUBSTANCE: method, a device and a carrier for long-term storage of information to determine a risk level, which indicates a risk of recurrence of cancer after treatment or a risk of progressing cancer or death, where the degree of risk is based on a combination of derived activities of two or more cell signaling pathways in tissue and/or cells, and/or body fluid of the subject. Cell signaling pathways comprise a Wnt pathway, an ER pathway and/or a HH pathway. Degree of risk is determined such that the said risk of the clinical event within a certain period of time decreases with increase in P_ER and increases with increasing max (P_Wnt, P_HH), where P_ER, P_Wnt and P_HH denote the derived activity of the ER path, Wnt path and HH path, respectively.

EFFECT: presented group of inventions enables to determine the degree of risk of cancer recurrence after treatment, risk of progressing cancer or death.

12 cl, 7 dwg, 14 tbl, 6 ex