NANOMATERIAL FOR TARGETED DELIVERY OF ANTICANCER AGENTS AND ANTICANCER AGENTS BASED ON IT Russian patent published in 2017 - IPC A61K31/704 A61K47/30 B82Y5/00 A61P35/00 

FIELD: medicine.

SUBSTANCE: group of inventions refers to the medicine, particularly, to the oncology and molecular biology, and reveals the nanomaterial for targeted delivery of an anticancer agent to a tumor localization area. The nanomaterial includes particles of magnetite covered with a hydrophilic polymer containing a vector fragment, as its constituent, able to bind to sugars on the surface of cancer cells and selected from a group of plant lectin. Additionally, an anticancer agent is proposed, which provides its targeted delivery to a cancer localization area, containing the mixture of the said nanomaterial with a cytotoxic agent.

EFFECT: group of inventions allows effective delivery of cytotoxic agents to cancer cells by means of the vector fragment, viscumin, accompanied by release of the agent impacted by the external magnetic field or without it. This provides diagnostics and treatment of tumors, as well as reduction of total toxicity of cytostatic agents applied in medical practice, such as doxorubicin, paclitaxel.

16 cl, 8 ex