FIELD: medicine.
SUBSTANCE: spherical nanoparticles of boron nitride with size 50-300 nm with developed external surface are synthesised by method of chemical precipitation from gas phase with application of reaction and transport gases, as well as powder mixtures, which consist of amorphous boron and reagent-oxidants, dispersion of agglomerates of obtained boron nitride nanoparticles by method of ultrasonic processing, saturation of boron nitride nanoparticles with anti-tumour medication by method of sorption and washing of nanoparticles in distilled water are carried out.
EFFECT: method makes it possible to improve efficiency of anti-tumour chemotherapy due to increased activity of absorption of nanocontainers with anti-tumour medication by cells, prevention of toxicity of nanocontainers for cells.
19 cl, 2 ex, 2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR OBTAINING NANOPARTICLES OF POLYSTYRENE ION EXCHANGERS FOR DELIVERY OF ANTITUMOUR PREPARATIONS | 2016 |
|
RU2635865C1 |
| METHOD OF PRODUCING A COMPOSITION FOR BORON-NEUTRON CAPTURE THERAPY OF MALIGNANT TUMORS (VERSIONS) | 2019 |
|
RU2720458C1 |
| METHOD OF PRODUCING NANOCONTAINERS FOR CHEMOTHERAPEUTIC ANTICANCER DRUGS | 2018 |
|
RU2722745C1 |
| NANOMATERIAL FOR TARGETED DELIVERY OF ANTICANCER AGENTS AND ANTICANCER AGENTS BASED ON IT | 2016 |
|
RU2610170C1 |
| METHOD FOR BORON NITRIDE NANOTUBES PRODUCTION | 2016 |
|
RU2614012C1 |
| METHOD FOR PRODUCING NANOSTRUCTURED DOUBLE HYDROXIDES BASED ON ALUMINIUM AND ALKALINE EARTH METALS SUCH AS MAGNESIUM OR CALCIUM, EXHIBITING THE PROPERTY OF INCREASING THE pH OF A CELLULAR MEDIUM, AND NANOSTRUCTURES PRODUCED THEREBY | 2020 |
|
RU2758671C1 |
| METHOD FOR PREPARING PHARMACEUTICALLY ACCEPTABLE DOSAGE FORMS AND USING THEM IN COMBINED CHEMOTHERAPY AND PHOTODYNAMIC THERAPY OF MALIGNANT NEOPLASMS | 2023 |
|
RU2822629C1 |
| MEDICINAL PRODUCT FOR TREATMENT OF BREAST CANCER | 2017 |
|
RU2657545C1 |
| ANTITUMOUR AGENT BASED ON BIODEGRADABLE NANOPARTICLES CARRYING A RECOMBINANT HUMAN TUMOR NECROSIS FACTOR ALPHA | 2018 |
|
RU2691938C1 |
| AGGLOMERATED METAL OXYHYDROXIDES AND USE THEREOF | 2013 |
|
RU2560432C2 |
