COMPOSITION CONTAINING DISULPHIDE POLYCATIONIC AMPHIPHILE WITH NEUTRAL PHOSPHOLIPIDE AND METHOD FOR PRODUCING THEREOF Russian patent published in 2017 - IPC C07J31/00 A61K47/28 

Abstract RU 2610271 C1

FIELD: chemistry.

SUBSTANCE: invention relates to disulphide polycationic amphiphile 1,32-bis(cholest-5-en-3-yloxycarbonylamino)-8,25-dioxo-3,4,21,22-tetrathia-7,10,14,19,23,26-hexaasedotriacontane tetrahydrochloride:

The invention also relates to a composition for extended and short nucleic acids delivery to mammalian cells and to a method for producing the composition for extended and short nucleic acids delivery.

EFFECT: disulphide polycationic amphiphile, capable of efficient delivery of nucleic acids to cells in the presence of serum in a growth medium.

4 cl, 2 tbl, 4 ex

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RU 2 610 271 C1

Authors

Puchkov Pavel Anatolevich

Shmendel Elena Vasilevna

Morozova Nina Georgievna

Maslov Mikhail Aleksandrovich

Zenkova Marina Arkadevna

Dates

2017-02-08Published

2016-03-02Filed