COMPOSITION FOR DELIVERING NUCLEIC ACIDS INTO CELLS OF MAMMALS Russian patent published in 2011 - IPC A61K47/18 A61K47/22 

Abstract RU 2423147 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to medicine and deals with composition for delivering nucleic acids into cells of mammals in presence and absence of serum in growth medium. Composition includes polycationic amphiphile and neutral phospholipid, and forms complex with nucleic acid.

EFFECT: invention ensures high efficiency and low toxicity of composition and ability to deliver to cells of mammals both short and extended nucleic acids.

1 cl, 4 ex, 2 dwg, 3 tbl

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RU 2 423 147 C1

Authors

Zenkova Marina Arkad'Evna

Kabilova Tat'Jana Olegovna

Maslov Mikhail Aleksandrovich

Morozova Nina Georgievna

Petukhov Ivan Alekseevich

Serebrennikova Galina Andreevna

Dates

2011-07-10Published

2010-03-22Filed