FIELD: medicine, pharmacy.
SUBSTANCE: invention refers to medicine, namely to urology and oncology. Intravenous injection of "Photoditazine" photosensitizer doses of 0.8-1.2 mg/kg of body weight is performed. In 2 hours after injection, the pathologic nidus is exposed to laser radiation with a wavelength of 662 nm. The power density is 200-400 mW/cm2. Irradiation is carried out by fractions with total radiation dose of 250 J/cm2. An irradiation session is divided into two equal portions at intervals of 20-30 minutes. The method allows to increase the efficiency of treatment, maintain anatomical and functional integrity of the body with a good cosmetic effect due to 2 stages of an irradiation session, which ensures prevention of photosensitizer burnout; the first fraction of irradiation provides photodynamic destruction of tumor cells, the second fraction - the destruction of organ blood flow.
EFFECT: invention can be used for photodynamic therapy of surface cancer and precancerous conditions of penis.
2 ex
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Authors
Dates
2017-03-01—Published
2015-10-01—Filed