METHOD FOR ESTIMATING THREAT FOR FORMATION OF FETUS ORGANS IN CASE OF INCREASE OF 17-HYDROXYPROGESTERON CONTENT IN PLACENTA IN THIRD GESTATION TRIMESTER IN CASE OF EXACERBATION OF CYTOMEGALOVIRUS INFECTION Russian patent published in 2017 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to laboratory diagnostics, and can be used for estimation of threat for formation of fetus organs in case of increase of content of 17-hydroxyprogesteron in case of exacerbation of cytomegalovirus infection in the third gestation trimester. For this purpose activity of 17-hydroxyprogesterondehydrogenase on cuts of placenta tissue is determined by histochemical method and titre of antibodies to cytomegalovirus in pheripheral blood is measured; in case of growth of titre of class G antibodies to cytomegalovirus 1:1600 and increase of activity of response to 17-hydroxyprogesterondehydrogenase in syncytiotrophoblast of placenta villi to 42.6±3.08 pixel/mcm ² threat for formation of fetus organs in gestation period appears.

EFFECT: method being simple for implementation makes it possible to estimate threat for formation of fetus organs.

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