2-CHLORO-4-[1-(4-FLUOROPHENYL)-2,5-DIMETHYL-1H-IMIDAZOL-4-YLETHINYL]-PYRIDINE MONOSULPHATE SALT AND CRYSTALLINE FORM THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAID SALT AND PRODUCTION METHOD THEREOF Russian patent published in 2012 - IPC C07D401/06 A61K31/4439 A61P25/00 

Abstract RU 2460728 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a 2-chloro-4-[1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-ylethinyl]-pyridine monosulphate salt and crystalline forms thereof. The present invention also relates to a method of producing said salt and a pharmaceutical composition based on said salt.

EFFECT: novel compounds have activity with respect to the mGluR5 receptor.

20 cl, 11 dwg, 3 tbl, 4 ex

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RU 2 460 728 C2

Authors

Kliri Tomas P.

Glomme Aleksandr

Grassmann Olaf

Kvan Sjan'-Min

Mejer Roland

Miller Dorin

Mog Regina

Rorer Frantsiska E.

Jang Dzhejson

Dates

2012-09-10Published

2007-12-11Filed