FIELD: chemistry.
SUBSTANCE: invention relates to a 2-chloro-4-[1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-ylethinyl]-pyridine monosulphate salt and crystalline forms thereof. The present invention also relates to a method of producing said salt and a pharmaceutical composition based on said salt.
EFFECT: novel compounds have activity with respect to the mGluR5 receptor.
20 cl, 11 dwg, 3 tbl, 4 ex
Title |
Year |
Author |
Number |
NOVEL CRYSTALLINE SALT FORM 3-(1,2,4-TRIAZOLO[4,3-A]PYRIDIN-3-YLETHYNYL)-4-METHYL-N-(4-((4-METHYLPIPERAZIN-1-YL)METHYL)-3-TRIFLUOROMETHYLPHENYL) BENZAMIDE FOR MEDICAL APPLICATION |
2016 |
- Chilov Germes Grigorevich
- Titov Ilya Yurevich
|
RU2652992C2 |
CRYSTALLINE FORMS OF 1-(5'-(5-(3,5-DICHLORO-4-FLUOROPHENYL)-5-(TRIFLUOROMETHYL)-4,5-DIHYDROISOXAZOL-3-YL)-3'H-SPIRO[AZETIDINE-3,1'-ISOBENZOFURAN]-1-YL)-2-(METHYLSULFONYL)ETHANONE |
2013 |
- Billen Denis
- Bechmejer Metyu Dzhozef
- Vanderroest Ronald Dzhej
|
RU2614978C2 |
NOVEL CRYSTALLINE FORMS OF SODIUM SALT OF (4-{4-[5-(6-TRIFLUOROMETHYL-PYRIDIN-3-YLAMINO)PYRIDIN-2-YL]PHENYL}CYCLOHEXYL) ACETIC ACID |
2011 |
|
RU2612556C2 |
CRYSTALS OF CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF |
2017 |
- Takahashi Hirozumi
- Baba Yoko
- Morita Yasuhiro
- Iseki Katsuhiko
- Izumimoto Naoki
|
RU2719384C1 |
POLYMORPHOUS AND AMORPHOUS FORMS OF {2-FLUORINE-5-[3-((E)-2-PYRIDINE-2-ILVINYL)-1N-INDAZOLE-6-ILAMINE]PHENYL}AMIDE 2, 5-DIMETHYL-2N-PYRAZOLE-3-CARBONIC ACID |
2005 |
- E Tsjan'
- Zuk Skott Ehdvard
- Oullet Majkl Allen
- Khettinger Donald Nikolas
- Srirangam Dzhajaram Kasturi
- Kanija Robert Stiven
- Saeed Nabil' Lauze
- Uajtlin Mehtt'Ju Dehvid
- Mitchell Mark Brajan
|
RU2324692C1 |
INDAZOLE DERIVATIVE SALTS AND THEIR CRYSTALS |
2017 |
|
RU2747399C2 |
(S)-OMEPRAZOLE POTASSIUM SALT, METHOD FOR IT PREPARING AND PHARMACEUTICAL PREPARATION BASED ON THEREOF |
2000 |
|
RU2237666C2 |
4-METHYL-N-[3-4-METHYLIMIDAZOL-1-YL)-5-TRIFLUOROMETHYLPHENYL]-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)BENZAMIDE SALTS |
2006 |
- Manli Pol U.
- Shi Vehn'Chun
- Satton Pol Allen
- Karpinski Petr Kh.
- Vu Rain
- Monn'E Stefani
- Brotsio Jerg
|
RU2509767C1 |
SPIRO COMPOUNDS AS ANTAGONISTS OF MELANOCORTIN 4 RECEPTORS AND THEIR USE |
2021 |
- Batler, Kristofer Rajan
- Garnsi, Mishel Rene
- Odzhilvi, Kevin Aleksander
- Polivkova, Yana
- Semmons, Mettyu Forrest
- Smit, Aaron Kristofer
- Yan, Tsingyuj
|
RU2813541C1 |
CRYSTALLINE POLYMORPHYL OF 4-[5-(PYRIDINE-4-YL)-1H-1,2,4-TRIAZOL-3-YL]-PYRIDINE-2-CARBONITRILE AND METHOD OF ITS OBTAINING |
2013 |
- Ivabuti Josiyuki
- Miyata Satikho
- Sato Takakhiro
- Uda Dzunitiro
- Kandou Takamitsu
- Inoue Tadasi
- Nakano Khiroyuki
|
RU2639149C2 |