FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology. Disclosed is method for producing composition containing IgM immunoglobulins from plasma fractions. Also described is antibody preparation produced by such method, and use of this preparation for therapy of patients or preparing medicine for treating immunological disorders and bacterial infections.
EFFECT: method involves providing plasma fraction in form of solution containing immunoglobulins, mixing solution with octanoic acid, treatment of mixed solution in vibromixer for deposition of contaminating proteins, and separation of deposited proteins from solution to obtain composition containing IgM from immunoglobulins.
30 cl, 1 dwg, 11 tbl, 9 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PRODUCING IMMUNOGLOBULIN COMPOSITION | 2011 |
|
RU2765738C2 |
| ANTIBODY PREPARATIONS | 2011 |
|
RU2749732C2 |
| PREPARATIONS OF ANTIBODIES | 2011 |
|
RU2617532C2 |
| METHOD FOR PRODUCING IMMUNOGLOBULIN FOR INTRAVENOUS INTRODUCTION OF IMMUNOGLOBULIN M ENRICHED PREPARATION, AND PREPARATION PREPARED BY SUCH METHOD | 2010 |
|
RU2470664C2 |
| METHOD OF PRODUCING COMPLEX OF IgG, IgM AND IgA IMMUNOGLOBULINS FOR INTRAVENOUS ADMINISTRATION | 2012 |
|
RU2492176C1 |
| HUMAN IMMUNOGLOBULIN PREPARATION AGAINST CYTOMEGALOVIRUS FOR INTRAVENOUS INTRODUCTION AND METHOD OF ITS OBTAINING | 2009 |
|
RU2404250C1 |
| METHOD OF IGM-CONTAINING IMMUNOGLOBULIN CONCENTRATE PREPARING | 1999 |
|
RU2158136C1 |
| METHOD OF PREPARING IMMUNOGLOBULINS FOR INTRAVENOUS ADMINISTRATION AND OTHER IMMUNOGLOBULIN PREPARATIONS | 1999 |
|
RU2197500C2 |
| METHOD OF PREPARATION OF VIRUS-INACTIVATED SOLUTIONS OF IMMUNOGLOBULINS | 2007 |
|
RU2352358C1 |
| METHOD FOR THE PRODUCTION OF IMMUNOGLOBULINS FOR INTRAVENOUS ADMINISTRATION | 2019 |
|
RU2742655C1 |
