METHOD FOR FETAL GROWTH RETARDATION SYNDROME PREDICTION IN THE THIRD TRIMESTER OF GESTATION IN CASE OF CHRONIC BRONCHITIS EXACERBATION FOR FEMALES WITH A (H3N2) INFLUENZA IN THEIR SECOND TRIMESTER OF GESTATION Russian patent published in 2017 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: for fetal growth retardation prediction in the third trimester of gestation during chronic simple bronchitis exacerbation caused by A(H3N2) influenza, the level of influenza virus antibodies in the blood serum of women in the second trimester of pregnancy, obtained on day 21-24 of the disease is determined, and its change is estimated in comparison with the serum obtained on day 12-14 of the disease, scoring: 1 point - no growth of antibody titer; 2 points - antibody titer growth by 2 times; 3 points - antibody titer growth by 4 times; 4 points - antibody titer growth by over 4 times (A), the content of midmolecular peptides is evaluated in the blood plasma on day 21-24 of the disease (u op. pl.) (B), tumor necrosis factor concentration in the serum (pg/ml) is determined on day 21-24 of the disease (C), and then the discriminant function is calculated using the discriminant equation: D = -2.790×A-149.616×B-0.121×C; and at D equal to or more than -50.23, absence of fetal growth retardation is predicted, at D less than -50.23, development of fetal growth retardation is predicted.

EFFECT: method allows to perform reasonable and timely medical and preventive measures aimed at fetal growth retardation syndrome prevention at simplicity of its execution.

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