FIELD: medicine.
SUBSTANCE: for prediction of fetus intrauterine infection for women in the second trimester of gestation during exacerbation of chronic simple bronchitis caused by A (H3N2) influenza, the titer of antibodies to A (H3N2) influenza virus is determined in the blood serum obtained on day 21-24 of the disease, and its change is evaluated compared to the serum obtained on day 12-14 of the disease, scoring: 1 point - no growth of antibody titer; 2 points - antibody titer growth by 2 times; 3 points - antibody titer growth by 4 times; 4 points - antibody titer growth by over 4 times (A), interferon concentrationγ (Pg/ml) is evaluated (B), circulating immune complexes (CIC) content (u op. pl.) is determined, (C), and then the discriminant function is calculated using the discriminant equation: D = -2.115×A-0.324×B-328.250×C, and at D equal to or greater than -82.67, absence of fetus intrauterine infection is predicted, and at D less than -82.67, fetus intrauterine infection is predicted.
EFFECT: method allows to perform reasonable and timely medical and preventive measures aimed at fetal infection prevention at simplicity of its execution.
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Authors
Dates
2017-03-21—Published
2016-03-02—Filed