METHOD FOR PREMATURE BIRTH PREDICTION IN SECOND TRIMESTER OF GESTATION ASSOCIATED WITH PREVIOUS INFLUENZA A(H3N2) IN FIRST TRIMESTER OF PREGNANCY COMPLICATED BY RETROCHORIAL HEMATOMA Russian patent published in 2018 - IPC A61B5/00 A61B8/00 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention can be used for premature birth prediction in the second trimester of gestation associated with previous influenza A(H3N2) in the first trimester of pregnancy complicated by retrochorial hematoma. In the first serum, the level of antibodies to the influenza virus A(H3N2) is determined (A). The concentration of interferon-γ (pg/ml) is established (B). The condition of the villous chorion in is assessed in points (C). The severity of the threat of miscarriage is determined in points (N). The prognosis for premature birth development is determined by the value of the discriminant function (D) with a boundary value of -22.36. At D equal to or greater than the boundary value, a normal course of pregnancy is predicted. At D less than the boundary value, premature birth in the second trimester of gestation is predicted.

EFFECT: method allows to accurately predict premature birth in the second trimester of gestation in women after the influenza in the first trimester of pregnancy, complicated by retrochorial hematoma due to assessment of the most meaningful indicators.

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