METHOD FOR SUBSTITUTED QUINOLINES PRODUCTION FROM ANILINE, 1,2-DIOLS AND CCL4 UNDER IRON CATALYSTS Russian patent published in 2017 - IPC C07D215/04 C07D215/20 

FIELD: chemistry.

SUBSTANCE: invention relates to a method for preparation of substituted quinolines of the formula shown below , where R¹=CH₃, R² and R³=H; R¹=CH₂CH₃, R²=CH₃ and R³=H; R¹=CH₂CH₃, R²=H and R³=CH₃; R¹=CH₂CH₂CH₃, R²=CH₂CH₃ and R³=H; X=H, o-CH₃, "м"-CH₃, "п"-CH₃, o-C₂H₅, o-Cl, "м"-Cl, "п"-Cl, "п"-OMe, o-OH, from aniline, wherein the substituted anilines of formula XC₆H₄NH₂ where X is as defined above, is reacted with 1,2-diols (1,2-ethylene glycol, 1,2-propanediol or 1,2-butanediol) and CCl₄ in the presence of a catalyst selected from FeCl₃⋅6H₂O, FeCl₃, FeCl₂^⋅4H₂O, Fe(C₅H₅)₂, Fe(acac)₃, Fe(OAc)₂ and Fe₂(CO)₉, at a molar ratio [catalyst]:[aniline]:[CCl₄]:[1,2-diol] = 1:100: 200:400, at 150 °C for 8 hours.

EFFECT: process for preparation of quinoline derivatives that are raw materials for corrosion inhibitors, dyes and medicines production from available initial reactants.

1 tbl, 35 ex