METHOD FOR EYE TISSUE HYPOXIC DAMAGE SIMULATION WITH APOPTOSIS ACTIVATION Russian patent published in 2017 - IPC G09B23/28 

FIELD: medicine.

SUBSTANCE: to simulate the hypoxic damage of eye and retina surface tissues, which leads to apoptosis activation, the experimental animal is exposed to the physical factor. Histological eye tissue samples are obtained and cells being in the apoptosis state are identified therein. The animal is placed into a sealed 0.10-0.15 m³ chamber, where nitrogen gas is delivered at a rate of 2.0-2.4 liter/min, until seizures begin in the experimental animal.

EFFECT: possibility of selective activation of apoptotic processes simultaneously in the eye and retina tissues to assess hypoxia among the factors that cause dry eye syndrome and retinopathy.

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