METHOD FOR BIFUNCTIONAL AFFINITY SORBENT PREPARATION FOR CHROMATOGRAPHIC PURIFICATION OF FLUORESCENT IMMUNOGLOBULINS Russian patent published in 2017 - IPC G01N33/53 

Abstract RU 2614960 C1

FIELD: medicine.

SUBSTANCE: invention concerns a method for obtaining a bifunctional affinity sorbent for chromatographic purification of fluorescent immunoglobulins by neosmectin immobilization with heterologous antigens, which give cross-reactions with immunoglobulins, wherein a water-soluble antigen is added to the sorbent, exposure is carried out, the unbound antigen is washed away, the pH is adjusted and one-step purification of fluorescent immunoglobulins from unbound FITC and heterologous antibodies is performed with the control of immunological parameters of finished products in the IFA.

EFFECT: invention ensures effective purification of fluorescent immunoglobulins from unbound dye and heterologous antibodies.

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RU 2 614 960 C1

Authors

Zharnikova Tatyana Vladimirovna

Zharnikova Irina Viktorovna

Taran Tatyana Viktorovna

Dates

2017-03-31Published

2016-04-18Filed