METHOD FOR OXYHEMOGLOBIN REDUCTION ASSESSMENT IN CASE OF INDUCING EFFECT OF CMV INFECTION ON RED BLOOD CELLS HEMOGLOBIN STRUCTURE, LEADING TO HEINZ'S BODIES FORMATION Russian patent published in 2017 - IPC G01N33/48 G01N33/49 G01N33/50 

FIELD: medicine.

SUBSTANCE: method for hemolytic anemia development determination for pregnant women in the third trimester of gestation in case of chronic cytomegalovirus infection exacerbation includes determination of the cytomegalovirus antibody titer in the peripheral blood, Heinz's bodies determination in erythrocytes, glutathione reductase and oxyhemoglobin content determination, and with an increase in the cytomegalovirus antibody titer to 1:1600, reduction in glutathione reductase erythrocytes to 3.95±0.06 U/gHb, Heinz's bodies presence in erythrocytes of 2 to 5 per each erythrocyte and oxyhemoglobin reduction to 84.0±2.9%, hemolytic anemia is developed in a pregnant woman.

EFFECT: method can effectively detect hemolytic anemia development in pregnant women in the third trimester of gestation at chronic cytomegalovirus infection exacerbation.

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