ANTIBODIES TO HUMAN CSF-1R AND USE THEREOF Russian patent published in 2017 - IPC C07K16/28 A61K39/395 A61P35/00 A61P37/00 C12N15/13 C12N15/63

Abstract RU 2617966 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to biochemistry. Antibody against human macrophage colony-stimulating factor 1 receptor (CSF-1R) is presented. Invention also relates to method of producing above antibody, pharmaceutical composition and use of above antibody.

EFFECT: invention enables inhibiting binding of CSF-1 with CSF-1R and can be used for treating cancer, bone loss, inflammatory diseases, as well as for preventing or treating metastases.

12 cl, 1 dwg, 7 tbl, 8 ex

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RU 2 617 966 C2

Authors

Georg Fertig

Aleksander Fidler

Klaus Kalutsa

Marlene Tomas

Karola Ris

Shtefan Zeeber

Dates

2017-04-28—Published

2011-03-03—Filed