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2 569 461

(13)

(51)

IPC

C07K16/22(2006-01-01)

A61K39/395(2006-01-01)

(21) (22)

Application

2013140625/10, 2009-12-14

(24)

Start date

2009-12-14

(22)

Actual filing date

2009-12-14

(45)

Published

2015-11-27

(72)

Inventor

Brinkmann Ul'RikhGrip Remko-AlbertKalutsa KlausKavl'E AnitaKlajn KristianRegula Jerg TomasShojer Verner

(73)

Holder

F. Hoffmann-La Roche Ag

ANTIBODIES AGAINST HUMAN ANGIOPOIETIN-2 Russian patent published in 2015 - IPC C07K16/22 A61K39/395

Abstract RU 2569461 C2

FIELD: chemistry.

SUBSTANCE: invention relates to biochemistry, particularly to antibodies against human angiopoietin-2, nucleic acids encoding said antibodies and host cells, as well as use of the antibodies to produce a medicinal agent for preventing metastasis, treating cancer or vascular diseases.

EFFECT: invention increases specificity, lowers toxicity and improves pharmacokinetic properties of antibodies against human angiopoietin-2.

11 cl, 13 dwg, 10 tbl, 9 ex

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RU 2 569 461 C2

Authors

Brinkmann Ul'Rikh

Grip Remko-Albert

Kalutsa Klaus

Kavl'E Anita

Klajn Kristian

Regula Jerg Tomas

Shojer Verner

Dates

2015-11-27—Published

2009-12-14—Filed