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(19)

RU

(11)

2 542 382

(13)

C2

(51)

IPC

C07K16/22(2006-01-01)

A61K39/395(2006-01-01)

C12N15/27(2006-01-01)

C12N15/63(2006-01-01)

C12N5/10(2006-01-01)

A61P35/00(2006-01-01)

A61P9/00(2006-01-01)

(21) (22)

Application

2011117410/10, 2009-10-07

(24)

Start date

2009-10-07

(22)

Actual filing date

2009-10-07

(45)

Published

2015-02-20

(72)

Inventor

Monika BehnerUl'Rikh BrinkmannGi ZhorzhRemko-Al'Bert GriepZabine Imkhof-JungAnita Kavl'EKhubert KettenbergerKristian KlajnJerg Tomas RegulaVol'Fgang ShehferJurgen Mikhaehl' ShantserVerner ShojerShtefan ZeeberMarkus Tomas

(73)

Holder

F.Khoffmann-Lja Rosh Ag

BISPECIFIC ANTI-VEGF/ANTI-ANG-2 ANTIBODIES Russian patent published in 2015 - IPC C07K16/22 A61K39/395 C12N15/27 C12N15/63 C12N5/10 A61P35/00 A61P9/00 

Abstract RU 2542382 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to biotechnology and immunology.

EFFECT: bispecific anti-human vascular endothelial growth factor VEGF and human angiopoietin-2 ANG-2 antibodies, methods for producing them, pharmaceutical compositions containing the above antibodies, and using them are described.

13 cl, 26 dwg, 15 tbl, 19 ex

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RU 2 542 382 C2

Authors

Monika Behner

Ul'Rikh Brinkmann

Gi Zhorzh

Remko-Al'Bert Griep

Zabine Imkhof-Jung

Anita Kavl'E

Khubert Kettenberger

Kristian Klajn

Jerg Tomas Regula

Vol'Fgang Shehfer

Jurgen Mikhaehl' Shantser

Verner Shojer

Shtefan Zeeber

Markus Tomas

Dates

2015-02-20—Published

2009-10-07—Filed

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