PSEUDOPEPTIDES OF SALTS THEREOF, METHODS OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION Russian patent published in 1998 - IPC

Abstract RU 2106356 C1

FIELD: medicine, more particularly prophylacsis and medical treatment of thrombosis. SUBSTANCE: present invention describes pseudopeptides or salts thereof of formula I: wherein R1 is COOH, COO L1: X is CH2, or R1 and X together are ; Y is (CH2)m, m is 1 or 2, A is -CO-(CH2)p-C6H4-C-(=NH)NH2 wherein p is 0 or 1; B is -CO-(CH2)q-R3 wherein q is 1 or 2; R3 is (C1-C4) alkyl, 1-adamantyl, (C1-C4) alkoxyphenyl or B is -SO2-(CH2)r-R4 wherein is 0,1 or 2; R4 = n-(C1-C4) is alkoxyphenyl. Present invention also describes two methods of preparing compounds I and pharmaceutical composition comprising as active ingredient pseudopeptide of formula I or salt thereof in effective amount. EFFECT: improved properties of the pharmaceutical composition. 9 cl, 2 tbl

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RU 2 106 356 C1

Authors

Georg Kottirsh[De]

Rajner Metternikh[De]

Dates

1998-03-10Published

1993-03-09Filed