FIELD: medicine.
SUBSTANCE: expression level of TLR2 and TLR9 Toll-like receptor genes is determined in scrapes of nose mucous tunic using a real time polymerase chain reaction. When the expression levels of the mentioned genes are increased at least by 20 and 9 times, respectively, compared to their level established for healthy children, innate immunity abnormality is diagnosed, resulting in exacerbation of bronchial asthma on the background of acute respiratory infection.
EFFECT: effective non-invasive method of assessing the innate immunity in children with bronchial asthma, while increasing the reliability and specificity of diagnostics.
3 ex
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