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2 618 425

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IPC

A61K39/02(2006-01-01)

A61K31/65(2006-01-01)

A61P31/04(2006-01-01)

(21) (22)

Application

2016104723, 2016-02-11

(24)

Start date

2016-02-11

(22)

Actual filing date

2016-02-11

(45)

Published

2017-05-03

(72)

Inventor

Lebedeva Irina AndreevnaZhukova Svetlana IvanovnaRotov Konstantin AleksandrovichSnatenkov Evgenij Aleksandrovich

(73)

Holder

Federalnoe Kazennoe Uchrezhdenie Zdravookhraneniya Volgogradskij Nauchno-Issledovatelskij Protivochumnyj Institut Federalnoj Sluzhby Po Nadzoru V Sfere Zashchity Prav Potrebitelej I Blagopoluchiya Cheloveka

METHOD OF IMPROVING EFFICIENCY OF EMERGENCY PREVENTION OF EXPERIMENTAL MELIOIDOSIS Russian patent published in 2017 - IPC A61K39/02 A61K31/65 A61P31/04

Abstract RU 2618425 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, particularly to microbiology, and can be used in emergency prevention of experimental melioidosis infection. Method comprises combined administration of imunofan immunomodulator and a doxycycline antibiotic to an animal. The imunofan is administered to white mice twice intraperitoneally in a dose of 0.06 mcg per 1 day before and the following days after infection with 5LD₅₀ virulent strain of Burkholderia pseudomallei C-141, and doxycycline is used for 3 days after infection in amount of 2 mg per day, hypodermally. Survival indices of animals are calculated for 30 days after infection with determination of the percentage of surviving mice and the average life of dying mice.

EFFECT: invention provides emergency prevention of experimental melioidosis in animals.

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RU 2 618 425 C1

Authors

Lebedeva Irina Andreevna

Zhukova Svetlana Ivanovna

Rotov Konstantin Aleksandrovich

Snatenkov Evgenij Aleksandrovich

Dates

2017-05-03—Published

2016-02-11—Filed