MULTIPHASE COMPOSITIONS FOR ORAL CARE Russian patent published in 2017 - IPC A61K8/34 A61K8/49 A61K8/73 A61K8/02 A61Q11/00 

FIELD: medicine, pharmacy.

SUBSTANCE: group of inventions relates to production and application of oral care means. A dentifrice comprising the first composition and the second composition is proposed, wherein the compositions are coaxially extruded, so that the first composition glazes the second composition. At that, the first composition is opaque, and the second composition comprises soluble film fragments that are stable in composition but disintegrate during dentifrice application. The said film fragments comprise a pigment which is released during film fragments decay as the dentifrice is applied. Film fragments are fragments of a single-layer film comprising (by dry weight) (i) 20-60% of cellulose ethers selected from hydroxypropyl methylcellulose and mixtures thereof, (ii) 10-30% of propylene glycol; 5.1% of polysorbate 80, and 15-55% of pigment. Average thickness of film fragments is 0.5-5 mils. The method for production of the above dentifrice includes coaxial extrusion of the first composition and the second composition so that the first composition glazes the second composition. The method of teeth cleaning by the above means includes brushing until the film fragments are dissolved and the pigment provides a color signal of sufficient brushing to the user. A container for toothpaste is also proposed, which is amenable to coaxial extrusion of the first composition of dentifrice that is opaque, and the second composition of dentifrice that contains film fragments, so that the first composition glazes the second composition during extrusion to provide the above dentifrice.

EFFECT: application of the group of inventions provides stability of film fragments comprising high concentration of pigment in the composition, and at the same time, composition color change after brushing for a sufficient period of time.

9 cl, 6 tbl, 2 ex