ORGANOZINC COMPLEX, PREPARATION AND APPLICATION THEREOF Russian patent published in 2017 - IPC C07F3/06 

Abstract RU 2620376 C2

FIELD: pharmacy.

SUBSTANCE: method comprises interaction (A) of at least one organomagnesium complex with (B) at least one coordinating compound in combination with zinc ions and lithium ions and halide ions, at that, the said halide ions are selected from chloride, bromide and iodide. The said coordinating compound is represented by the formula (I): R1Tq, where each T is -CO2- or -O-, R1 represents an alkyl group containing from 4 to 8 carbon atoms, and "q" is a positive integer. Options of organozinc reagents preparation and coordinating zinc complex are also proposed.

EFFECT: these reagents can be used for preparation of organic compounds by cross-coupling Negishi reactions, or by reaction of oxidative aldehyde or ketone addition.

15 cl, 1 dwg, 3 tbl, 8 ex

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RU 2 620 376 C2

Authors

Knokhel Paul

Bernkhardt Sebastian

Manolikakes Georg

Dates

2017-05-25Published

2011-12-21Filed