HETEROCYCLIC DERIVATIVES AS RECEPTORS ASSOCIATED WITH TRACER AMINES (TAARS) Russian patent published in 2017 - IPC C07D413/10 C07D413/14 C07D471/04 A61K31/5377 A61P25/00

Abstract RU 2621050 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to compounds of formula and to pharmaceutical compositions based thereof.

EFFECT: new compounds are obtained with an affinity for the receptors to TAAR1 and can be used to treat depression, anxiety disorders, bipolar disorder, attention deficit/hyperactivity disorder, disorders caused by stress, psychotic disorders, schizophrenia, neurological diseases, Parkinson's disease, neurodegenerative disorders, Alzheimer's disease, epilepsy, migraine, hypertension, substance abuse, metabolic disorders, malnutrition, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, temperature homeostasis disorders, sleep disturbance, circadian dysregulation and cardiovascular disorders.

23 cl, 16 dwg, 1 tbl, 55 ex

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RU 2 621 050 C2

Authors

Gallej Guido

Gergle Annik

Norkross Rodzher

Pfliger Filipp

Dates

2017-05-31—Published

2013-01-08—Filed