DEVICE FOR TRANSDERMAL DRUG DELIVERY Russian patent published in 2017 - IPC A61M37/00 

FIELD: medicine.

SUBSTANCE: housing comprises the upper housing part and the lower housing part. The lower housing part defines a bottom surface with a skin attachment means for releasable fastening of the lower housing part to the user's skin. The upper part of the housing at least partially surrounds the central area of the device. Microneedle assembly is located in the central area. The reservoir is located in the central area. The reservoir communicates with the microneedle assembly with a possibility to transfer the liquid. The pushing member is located above the microneedle in the central area. The pushing member is arranged to provide a continuous bilateral force with a downward component, transmitted through the microneedle assemby and an upward component, transmitted through the means of attachment to skin. According to the second version, the transdermal drug delivery device includes an upper housing and a lower housing. The upper housing is attached to the lower housing defining a cavity. The lower housing defines a bottom surface with a skin attachment means for releasable fastening of the lower housing to the user's skin. The lower housing defines an opening and the surrounding microneedle assembly. The lower housing is separated from the microneedle assembly. The reservoir is located in the cavity and communicates with the microneedle assembly with a possibility to transfer the liquid. The pushing member is located within the cavity between the microneedle assembly and the upper housing. The pushing member is configured so as to be separated from the lower housing and provide (i) a continuous force comprising a downward component separated from the upper and lower housings, transmitted through the microneedle assembly onto the user's skin; (ii) a continuous force comprising an upward component separated from the microneedle assembly, transmitted to the lower housing. Method for transdermal drug delivery includes placement of the aforementioned transdermal drug delivery device adjacent to the skin; housing attachment to the skin by the skin attachment means; application of a continuous two-way force via transdermal delivery device by the pushing member with a downward component, transmitted through the microneedle assembly, and an upward component, transmitted through the means of skin attachment; and drug delivery through the microneedle assembly into or through the skin.

EFFECT: invention have improved ability to stably and efficiently deliver drugs through the patient's skin.

30 cl, 11 dwg