FIELD: pharmacology.
SUBSTANCE: invention relates to a new derivative of macrolide antibiotic oligomycin A - 2,3,16,17,18,19-hexahydrooligomycin A, its structure and its preparation method, as well as its application for treatment of diseases caused by Candida yeast fungi, since this compound has selective activity against a number of Candida spp. strains, and also a low (in comparison with the original oligomycin A) cytotoxicity and corresponds to formula
.
EFFECT: increased effeciency of compound application.
5 cl, 2 tbl, 2 ex
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Authors
Dates
2017-06-22—Published
2016-11-03—Filed