METHOD FOR PREDICTION OF RISK OF ARTERIAL HYPERTENSION DEVELOPMENT AND PROGRESS IN PATIENTS WITH CHRONIC HEPATITIS AT ANTI-VIRAL THERAPY BACKGROUND Russian patent published in 2017 - IPC A61B8/00 

FIELD: medicine.

SUBSTANCE: endothelial dysfunction is assessed non-invasively in dynamics before and 1 month after antiviral therapy initiation. The radial artery lumen is measured by ultrasonic scanning in B-mode by a linear sensor with 12 MHz capacity before and after radial artery occlusion with a tonometer cuff for 5 minutes with an interval of 1 minute. For this purpose, the cuff is placed on the limb above the radial artery lumen measurement site for 10 minutes and pressurized 20 mm Hg more than the patient's blood pressure. The risk of arterial hypertension development and progression is predicted by the endothelium ability to vasodilate after cuff application. At that, the percentage increase in the radial artery diameter is calculated after occlusion compared to the patient's baseline data prior to occlusion - the starting point. Risk factor for hypertension development and progression is the growth of the radial artery diameter less than 8.0% from the original diameter of the artery lumen prior to cuff application.

EFFECT: method allows to increase antiviral therapy safety, to exclude prediction subjectivity, to ensure study results storage on any medium.

3 dwg, 3 tbl, 2 ex