FIELD: pharmacology.
SUBSTANCE: solid pharmaceutical formulation as a pill, comprising 1-(3-(2-(1-benzothiophene-5-yl)ethoxy)propyl)azetidine-3-ol or a salt thereof in an amount of 30% to 90% The said pill also contains a component selected from mannitol, sorbitol and isomaltose in an amount of 6% to 60% by weight, and a disintegrant selected from the group consisting of cellulose derivatives, starch derivatives and polypyrrolidone derivatives in an amount of 3% to 10% by weight.
EFFECT: invention provides excellent solubility, hardness for dosage forms and increased stability in long-term storage.
11 cl, 15 ex, 5 tbl
Authors
Dates
2017-07-18—Published
2013-02-21—Filed