SOLID PHARMACEUTICAL COMPOSITION CONTAINING 1-(3-(2-(1-BENZOTHIOPHENE-5-YL)ETOXY)PROPYL)AZETIDINE-3-OL OR ITS SALT Russian patent published in 2017 - IPC A61K31/397 A61K31/428 A61K9/20 A61K9/28 A61K47/10 A61K47/32 A61K47/36 A61K47/38 

Abstract RU 2625767 C2

FIELD: pharmacology.

SUBSTANCE: solid pharmaceutical formulation as a pill, comprising 1-(3-(2-(1-benzothiophene-5-yl)ethoxy)propyl)azetidine-3-ol or a salt thereof in an amount of 30% to 90% The said pill also contains a component selected from mannitol, sorbitol and isomaltose in an amount of 6% to 60% by weight, and a disintegrant selected from the group consisting of cellulose derivatives, starch derivatives and polypyrrolidone derivatives in an amount of 3% to 10% by weight.

EFFECT: invention provides excellent solubility, hardness for dosage forms and increased stability in long-term storage.

11 cl, 15 ex, 5 tbl

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RU 2 625 767 C2

Authors

Inaba Khiroyuki

Nagata Mitsukhiro

Dates

2017-07-18Published

2013-02-21Filed