FIELD: pharmacology.
SUBSTANCE: inhibiting protein fucosylation a mammal is administered an effective amount of a fucose analogue selected from the group consisting of one of the following scab formulas (V) or (VI). Also, a pharmaceutical composition for inhibiting protein fucosylation in mammals is proposed.
EFFECT: inhibition of protein fucosylation, particularly, E-selectin fucosylation, which facilitates the suppression of autoimmunity.
11 cl, 9 dwg, 5 tbl, 8 ex
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