METHOD FOR PREDICTION OF FETAL GROWTH RETARDATION SYNDROME DEVELOPMENT AT TOBACCO SMOKING BACKGROUND Russian patent published in 2017 - IPC A61B5/26 A61B8/06 

FIELD: medicine.

SUBSTANCE: in the gestation period of 11-14 weeks, laser doppler flowmetry is used to determined one of the cutaneous microcirculation parameters, namely, the parameter characterizing the temporal variability of perfusion. According to the formula obtained by the binary logistic regression method, the prediction factor for fetal growth retardation syndrome is calculated: R=1/(1+e^-z), where R is the prediction factor for fetal growth retardation syndrome; e is a constant, base of the natural logarithm equal to 2.72; z is the degree of the inverse logarithm, calculated by the formula z=b₁⋅x₁+a, where b₁ is the regression factor, calculation of which is the task of binary logistic regression, which is equal to 5.121 in case of fetal growth retardation syndrome; x₁ is the value of the independent variable, namely the parameter characterizing the temporal variability of perfusion; a is a constant equal to -4.477 in case of fetal growth retardation syndrome. At R more than 0.5, development of complications of pregnancy, namely the fetal growth retardation syndrome, is predicted.

EFFECT: simplification and increased sensitivity of the method for prediction of fetal growth retardation syndrome at the tobacco smoking background.

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