FIELD: medicine.
SUBSTANCE: invention is a method for predicting tumour resistance to target therapy of cetuximab in patients with squamous cell carcinoma of the tongue and oral mucosa including a blood test, characterized in that two days before the initiation of a chemo-chemotherapy treatment with the inclusion of targeted cetuximab therapy in a patient with squamous cell carcinoma of the tongue And the mucosal bottom is determined by EGF, sEGFR, then the ratio of EGF/sEGFR is calculated and at a value of this ratio between 55.3-66.9 it is predicted that there is no resistance against Plaques to cetuximab therapy, and with the value of this indicator within 92.6-117.8 predict the presence of tumour resistance to cetuximab therapy.
EFFECT: early prognosis of tumour resistance to targeted therapy with cetuximab.
2 ex, 1 tbl
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|---|---|---|---|
| METHOD FOR PREDICTING THE EFFECTIVENESS OF THE TARGETED THERAPY WITH CETUXIMAB IN THE PATIENTS SUFFERING SQUAMOUS CELL CARCINOMA OF THE TONGUE AND ORAL MUCOSA | 2019 |
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