METHOD FOR PREDICTION OF EFFECTIVENESS OF CONSERVATIVE TREATMENT OF OROPHARYNGEAL SQUAMOUS CELL CARCINOMA Russian patent published in 2024 - IPC G16H50/30 G01N33/577 G01N1/30 

Abstract RU 2817324 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to oncology, and can be used for prediction of effectiveness of conservative treatment of oropharyngeal squamous cell carcinoma. Treatment is preceded by histological and immunohistochemical detection of tumour-infiltrating lymphocytes (TILs), markers p16, CD4 and CD8. If TILs are not less than 57.5%, CD4 is not less than 37.5%, CD8 is not less than 8.50% and p16 status is positive, regression of the primary tumour is predicted with conservative treatment.

EFFECT: method provides improved overall prognosis and quality of life of patients with oropharyngeal squamous cell carcinoma due to an individual approach to treatment, based on determination of molecular markers taking into account threshold values of their expression.

1 cl, 1 tbl, 2 ex

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RU 2 817 324 C1

Authors

Stukan Anastasiya Igorevna

Porkhanov Vladimir Alekseevich

Bodnya Vadim Nikolaevich

Chukhraj Olga Yurevna

Nefedova Elizaveta Andreevna

Dates

2024-04-15Published

2023-10-16Filed