FIELD: pharmacology.
SUBSTANCE: presented method comprises: (a) cooling of initial suspension containing lipid component and protein component from the temperature in the first temperature range to the temperature in the second temperature range; (b) heating of the cooled suspension of stage (a) from the temperature in the second temperature range to the temperature in the first temperature range; (c) cooling of the mentioned heated suspension of stage (b) from the temperature in the first temperature range to the temperature in the second temperature range; and (d) repeating of the stages (b) and (c) at least once to prepare lipoprotein complexes.
EFFECT: presented inventions can be used to prepare homogeneous pharmaceutically acceptable drugs with less risk of adverse events due to contaminations during their use.
51 cl, 59 dwg, 19 tbl, 9 ex
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Authors
Dates
2017-08-03—Published
2012-02-06—Filed