LIPOPROTEIN COMPLEXES AND THEIR PREPARATION AND APPLICATION Russian patent published in 2017 - IPC C07K14/775 A61K38/17 A61K45/00 A61P3/00 

Abstract RU 2627173 C2

FIELD: pharmacology.

SUBSTANCE: presented method comprises: (a) cooling of initial suspension containing lipid component and protein component from the temperature in the first temperature range to the temperature in the second temperature range; (b) heating of the cooled suspension of stage (a) from the temperature in the second temperature range to the temperature in the first temperature range; (c) cooling of the mentioned heated suspension of stage (b) from the temperature in the first temperature range to the temperature in the second temperature range; and (d) repeating of the stages (b) and (c) at least once to prepare lipoprotein complexes.

EFFECT: presented inventions can be used to prepare homogeneous pharmaceutically acceptable drugs with less risk of adverse events due to contaminations during their use.

51 cl, 59 dwg, 19 tbl, 9 ex

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RU 2 627 173 C2

Authors

Dasseux Jean-Louis

Oniciu Daniela Carmen

Ackermann Rose

Dates

2017-08-03Published

2012-02-06Filed