FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention relates to reconstituted high density lipoprotein (rHDL) formulations comprising an apolipoprotein, a lipid and a lyophilization stabiliser, as well as a process for their preparation. Implementation of the invention makes it possible to obtain a reconstituted high density lipoprotein formulation, characterised by reduced renal toxicity and good long-term stability, in particular, in a lyophilised form.
EFFECT: reconstituted HDL formulation is disclosed.
24 cl, 7 ex, 2 tbl, 21 dwg
Title |
Year |
Author |
Number |
TREATMENT OF MYOCARDIAL INFARCTION WITH REGENERATED HIGH-DENSITY LIPOPROTEIN |
2017 |
- Wright, Samuel
- Shear, Charles
- D'Andrea, Denise
- Gille, Andreas
- Duffy, Danielle
|
RU2798830C2 |
LIPOPROTEIN COMPLEXES AND THEIR PREPARATION AND APPLICATION |
2012 |
- Dasseux Jean-Louis
- Oniciu Daniela Carmen
- Ackermann Rose
|
RU2627173C2 |
USING LCAT FOR TREATING ANAEMIA AND RED BLOOD CELL DISORDERS |
2010 |
- Auerbakh Brjus
- Kraus Brajan
- Khomen Rejnold
|
RU2576838C2 |
PHARMACEUTICAL COMPOSITION NO CONTAINING PROTEINS AND PEPTIDES, METHOD OF TREATMENT OF HUMANS AND ANIMALS SUFFERING WITH ENDOTOXEMIA AND METHOD OF PROPHYLAXIS OF DISEASE |
1995 |
- Levin Dehniel M.
- Parker Tomas S.
- Rubin Ehlbert L.
- Gordon Brjus R.
- Saal Stjuart D.
|
RU2174839C2 |
TREATMENT AND PREVENTION METHOD OF GRAM-POSITIVE BACTERIA INDUCED DISEASES |
2006 |
- Levin Dehniel
- Parker Tomas S.
|
RU2391985C2 |
A-I APOLIPOPROTEIN MIMETICS |
2010 |
- Dasse,Zhan-Lui
- Shvendeman,Anna,Shenderova
- Chzhu,Linjuj
|
RU2532222C2 |
METHOD OF TREATING SEPSIS IN PATIENTS HAVING ALBUMIN, CHOLESTEROL AND HDL LEVELS EXCEEDING MINIMUM THRESHOLDS |
2013 |
- Levine Daniel M.
- Parker Thomas S.
- Gordon Bruce R.
- Saal Stuart D.
|
RU2571688C1 |
TREATMENT OF APOLIPOPROTEIN-A1 RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO APOLIPOPROTEIN-A1 |
2009 |
- Kollard Dzhozef
- Khorkova Olga
|
RU2604489C2 |
PROCESS FOR PREPARING APOLIPOPROTEIN A-I (APO A-I) |
2014 |
- Vuchitsa Ivonne
- Uorren Geri Li
|
RU2668831C2 |
PHARMACEUTICAL COMPOSITIONS CONTAINING EPA AND CARDIOVASCULAR DRUG, AND METHODS OF USING THEM |
2017 |
- Manku Mekhar
- Rou Dzhonatan
|
RU2746945C2 |