AMINO ACIDS COMPOSITION FOR METHANOL POISONING PREVENTION AND TREATMENT Russian patent published in 2017 - IPC A61K31/198 A61K31/401 A61K31/405 

Abstract RU 2627610 C2

FIELD: pharmacology.

SUBSTANCE: amino acid composition from a group of natural or synthetic hydrophobic compounds that are alcohol dehydrogenase (ADH) inhibitors and contain D- and L-amino acids in the following component ratio, wt %: tyrosine 10-19.5, valine 13-22, leucine 14-24, alanine 4.0-23.3, tryptophan 1.7-36, proline 9.2-19 as active ingredients for the detoxification of methanol.

EFFECT: composition acts as an antidote that completely removes acute methanol poisoning, possesses protective properties, exhibiting a pronounced inhibitory effect of ADH activity on methanol oxidation, and significantly reduces the amount of highly toxic secondary metabolites.

7 cl, 4 ex, 1 tbl

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RU 2 627 610 C2

Authors

Fakhrutdinov Anas Mintalibovich

Enikeev Ajrat Khasanovich

Ostrovskij David Isaakovich

Dates

2017-08-09Published

2015-10-15Filed