COMPOUNDS OF THIENOPYRIMIDINE Russian patent published in 2017 - IPC C07D495/04 C07D513/04 A61K31/519 A61P3/10 A61P17/06 A61P19/02 A61P25/28 A61P35/00 

Abstract RU 2637925 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to a compound of formula I:

,

where group A is independently monocyclic or bicyclic aryl or heteroaryl optionally substituted by one or more A'; each group A' is independently C1-6 alkyl, halogen, cyano or heteroaryl; group R1 is tetrahydropyranyl substituted with an amino group; or pharmaceutically acceptable salts thereof, which are SYK inhibitors and are useful for treatment of autoimmune and inflammatory diseases.

EFFECT: increased efficiency of treatment.

10 cl, 2 tbl, 25 ex

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RU 2 637 925 C2

Authors

Chen Shaotsin

Germann Jokhannes Kornelius

Le Nam T.

Lukas Metyu S.

Pedilla Fernando

Dates

2017-12-08Published

2013-01-07Filed