FIELD: chemistry.
SUBSTANCE: invention relates to a method for production of α thiocyanated derivatives β- dicarbonyl compounds of general formula 
, where R = alkyl C1-C6, unsubstituted or substituted benzyl, allyl, CH2)2COOEt, (CH2)2CN; R1 and R2=CH3 or OEt or R+R1=(CH2)4, which can be used as medicinal products (anti-cancer, anti-asthmatic, analgesic, anti-inflammatory, antipyretic) and pesticides. The method includes reacting of α-substituted β-dicarbonyl compounds of general formula 
, where R, R1 and R2 have the above values, with sodium thiocyanate in the presence of cerium (IV) ammonium nitrate. The process is carried out in an organic solvent at a temperature of 20-25°C and molar ratio α-substituted of β-dicarbonyl compound: sodium thiocyanate: cerium(IV) ammonium nitrate equal to 1:2-4:2-4, respectively.
EFFECT: method allows to increase the yield of target products, to shorten the process time, to abandon highly toxic reagents and additional stages, to expand the range of obtained compounds of general formula I.
18 ex
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